Acrivon Therapeutics

Acrivon Therapeutics Employees

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Acrivon Therapeutics Company Information

Acrivon Therapeutics is a biotechnology company focused on developing precision oncology medicines tailored to patients whose tumors are predicted to respond to specific treatments. The company employs its proprietary proteomics-based patient responder identification platform, Acrivon Predictive Precision Proteomics (AP3), to match treatments to patients. Acrivon’s lead candidate, ACR-368, is a selective small molecule inhibitor targeting CHK1 and CHK2, currently undergoing a potentially registrational Phase 2 trial across multiple tumor types. The FDA has granted Fast Track designation for ACR-368 as a monotherapy for patients with platinum-resistant ovarian or endometrial cancer. Additionally, the FDA awarded Breakthrough Device designation for the ACR-368 OncoSignature assay, which identifies ovarian cancer patients likely to benefit from ACR-368 treatment. The company is also developing internally-discovered preclinical stage pipeline programs, including ACR-2316, a selective dual WEE1/PKMYT1 inhibitor. Acrivon Therapeutics is headquartered in Watertown, Massachusetts, with additional operations in Lund, Sweden.

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