Adaptimmune

Adaptimmune Employees

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Adaptimmune Company Information

Adaptimmune is a biotechnology firm engaged in developing T-cell-based therapies aimed at treating cancer. The company utilizes a proprietary cell therapy platform to engineer a patient’s own cells to target and fight cancer, specifically solid tumors. Adaptimmune has recently submitted its first Biologics License Application (BLA) to the FDA for a T-cell therapy designed for solid tumors. The company’s pipeline includes multiple engineered T-cell therapies, each targeting different solid tumors. Adaptimmune’s manufacturing process involves leukapheresis and the delivery of affinity-enhanced TCRs (T-cell receptors), ensuring the production of therapeutic candidates under Good Manufacturing Practices (GMP). The company has established partnerships with several notable entities, including Alpine Immune Sciences, Genentech, and MD Anderson Cancer Center, to enhance its platform capabilities and accelerate the development of its products. Additionally, Adaptimmune supports patient organizations financially and engages in educational and awareness initiatives to further support cancer treatment advancements. The company operates out of offices in Oxfordshire and Stevenage in the UK, and Philadelphia in the US, with a dedicated GMP vector manufacturing space in the UK through an agreement with Cell and Gene Therapy Catapult.

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Affini-T Therapeutics, based in Watertown, MA, develops TCR-based immunotherapies for solid tumors, focusing on oncogenic mutations such as KRAS and p53.

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