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Affini-T Therapeutics
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Affini-T Therapeutics Employees
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Affini-T Therapeutics Company Information
Affini-T Therapeutics, located at 100 Forge Road, Watertown, MA 02472, specializes in the development of targeted TCR-based immunotherapies for treating solid tumors. The company’s research primarily targets oncogenic driver mutations, notably KRAS G12D and p53 R175H, which are significant in the pathology of many cancers. Affini-T Therapeutics utilizes innovative platforms including TAILOR™ for TCR discovery, TUNE™ for T cell engineering, and THRIVE™ for the manufacturing of cell products. At the American Association for Cancer Research (AACR) Annual Meeting 2024, the company presented preclinical data from its programs focusing on these mutations. Affini-T offers therapeutic modalities such as bispecific T Cell Engagers and autologous TCR-T cell therapies. The company is actively engaged in clinical trials aiming for approval from the U.S. Food and Drug Administration (FDA) and other regulatory bodies.
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