Rancho BioSciences

Rancho BioSciences provides a comprehensive suite of services including artificial intelligence (AI), machine learning (ML), natural language processing (NLP), bioinformatics, CDISC services, data integrity, data technology, data management, data empowerment & innovation, imaging data, knowledge mining, large language models (LLM), proteomics, publication services, quality control (QC) management services, quality assurance services, subject matter expertise, toxicology, and target reports. The company supports pharmaceutical and biotech companies, academic institutions, foundations, and government entities with data curation services. Rancho BioSciences works with various life science data types such as clinical trials, genomics, gene variants, assays, chemistry, microbiome, flow cytometry, and imaging data. The company is platform-agnostic and has experience formatting data for many commercial, internal, and public (open-source) platforms. They develop custom AI/ML models for predictive toxicology, survival analysis, cellular phenotype classification, and disease signature analysis, and validate the performance of these algorithms to ensure accuracy and reliability. Specializing in natural language querying (NLQ), Rancho BioSciences makes internal and public datasets easily accessible across large organizations. Their bioinformatics services include single-cell transcriptomic analysis, processing and analysis of multimodal data, genetic variant detection, and pathway analysis. They ensure data integrity and compliance with CDISC standards through their CDISC services. Rancho BioSciences supports all aspects of data services around biomedical research, drug discovery, and precision medicine, using both automated and manual services for data harmonization, aligning data to CDISC, OMOP, and other standard data models. Their terminology services include semantic data integration, customized terminology and ontology services, nomenclature mapping and cross-referencing, training and support services, and data enrichment. Combining deep scientific knowledge with technical expertise in software engineering, they provide both custom and off-the-shelf solutions. Their data management, data governance, and data modeling services are comprehensive. High-quality imaging data services include data modeling, data aggregation and curation, and data analysis & reports. Leveraging large language models (LLMs), they offer services such as natural language processing, information extraction, semantic search, prompt engineering, and fine-tuning. Rancho BioSciences also offers a suite of toxicology services tailored to client needs and provides automated target reports with detailed biological and disease information. They have developed tools like the categorization tool (CAT) and an automatic quality control (QC) tool to enhance project efficiency and data quality. Their internal portal with a searchable interface supports project acceleration by providing a curated inventory of resources. Additionally, they launched the Single-Cell Data Science Consortium and the Spatial Innovation Initiative (SII) to deliver harmonized single-cell and spatial transcriptomics datasets more quickly and cost-effectively.