Sixfold Bioscience
Sixfold Bioscience Employees
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Sixfold Bioscience Company Information
Sixfold Bioscience, headquartered in London, England, operates within the healthcare industry, specifically focusing on drug discovery and delivery. The company, which is part of the Y-Combinator W18 batch, employs a team of 27 professionals. Sixfold is dedicated to the commercialization of advanced drug delivery systems for RNA therapeutics, such as siRNAs for gene silencing and mRNAs for gene expression. Their flagship technology, Mergo®, is a programmable RNA tag that encodes RNA modifications to direct the delivery of therapeutics to specific cells. This approach integrates evolutionary principles with artificial intelligence to enhance the delivery mechanism, making it more natural and efficient compared to traditional methods that force entry into cells. Sixfold Bioscience utilizes a high-throughput system to produce over 100,000 Mergo® variants, leveraging innovative chemistry and lab automation. This capability allows for extensive testing and optimization through their platform, Evolver, which combines automation, scaled testing, and AI to refine RNA delivery processes. The company’s work represents a significant step forward in the field of RNA-based therapeutics, focusing on both gene silencing and expression.