Venatorx Pharmaceuticals
Venatorx Pharmaceuticals Employees
15 people indexed:
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Chitrananda Abeygunawardana
Vice President, Regulatory Affairs
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Christopher J. Burns
Founder, President and Chief Executive Officer
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Daniel C. Pevear
Founder and Senior Vice President, Biology and Grants Development
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Jason Burdette
Senior Vice President, CMC and Technical Operations
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Jennifer Nelson
Senior Vice President, Strategic Planning and Operations
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Venatorx Pharmaceuticals Company Information
Venatorx Pharmaceuticals, established in June 2010, is dedicated to the discovery and development of novel anti-infectives aimed at treating multi-drug-resistant bacterial infections and challenging viral infections. The company has built a robust in-house research and development organization and has filed over 120 patents. Venatorx’s lead asset, cefepime-taniborbactam, is an investigational antibiotic that has successfully completed a Phase 3 study in adults with complicated urinary tract infections (cUTI), including pyelonephritis, and is currently under FDA review. This asset has been granted Qualified Infectious Disease Product (QIDP) and Fast Track designations by the FDA and is also being developed for hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP). In 2022, BARDA awarded Venatorx a Project Bioshield contract worth up to $318 million for the development and procurement of cefepime-taniborbactam. Additionally, Venatorx is developing an oral BL/BLI antibacterial, ceftibuten-ledaborbactam etzadroxil, which will advance directly to a global Phase 3 cUTI clinical trial under a new BARDA contract. This compound is designed to treat infections caused by drug-resistant Enterobacterales and has shown positive results in Phase 1 clinical trials. Venatorx is also pursuing discovery-stage programs in both antiviral and antibacterial fields, including a novel class of non-beta-lactam Penicillin Binding Protein (PBP) inhibitors. The company has received equity investments from Abingworth, the AMR Action Fund, BioAdvance, Foresite Capital, and Versant Ventures, along with significant funding awards from the Wellcome Trust, BARDA, CARB-X, DTRA, and NIAID. Venatorx has established license and collaboration agreements with Everest Medicines, GARDP, and Roche. Recognized as one of the ‘Best Places to Work’ by the Philadelphia Business Journal multiple times, Venatorx continues to make significant strides in the field of anti-infective drug development.