High Alpha Innovation

High Alpha Innovation is a venture builder headquartered in Indianapolis, Indiana, that collaborates with large-scale organizations, universities, and entrepreneurs to co-create startups. The company helps corporate partners build sustainable and successful venture building operations through a unique approach to incentives, process, and governance. High Alpha Innovation works with leading research universities to provide a platform for university-born ideas, increasing the chance of success for higher education startups. Entrepreneurs joining its portfolio companies benefit from critical infrastructure, talent, services, and resources. The Fusion Advisor Network, a community of advisors, supports early-stage startups by sharing expertise and providing access to board, advisory, and investment opportunities. High Alpha Innovation hosts various events, including the Alloy Venture Building Summit, Alloy’s Masterclass, and Forge, to bring together venture builders, investors, and entrepreneurs. The company’s portfolio includes startups like Amplio, Vellum, and Athian, developed in partnership with organizations such as Koch Industries, IU Health, and Elanco. The Alloy Summit is a premier event for innovation and university strategy leaders, government agencies, venture investors, and founders. The company offers a Venture Building Masterclass to support corporations and universities in launching venture building capabilities. The annual Forge event is a founder’s summit that brings together co-founders from its portfolio for networking and learning. High Alpha Innovation employs a structured process for building startups, including sprint programs and venture studios. Their playbook focuses on cost-efficient innovation, accelerated learning, balance sheet funding, and access to world-class entrepreneurs. The company supports its startups from Day One, helping them execute their growth strategy through market traction, capable teams, and access to capital, enabling them to scale quickly in competitive markets.